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Combined Treatment with Interleukin-12 and Indomethacin Promotes Increased Resistance in BALB/c Mice with Established Leishmania major Infections

Following infection of susceptible BALB/c mice with Leishmania major, early production of interleukin-4 (IL-4) is associated with the development of a nonprotective Th2 response and the development of progressive disease. Treatment of mice with IL-12 at the time of infection can promote the activati...

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Detalhes bibliográficos
Main Authors: Li, Jian, Padigel, Udaikumar M., Scott, Phillip, Farrell, Jay P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC128357/
https://ncbi.nlm.nih.gov/pubmed/12228301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.10.5715-5720.2002
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