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Requirement for CD40-CD40 Ligand Interaction for Elimination of Cryptosporidium parvum from Mice

Mice with disrupted genes for CD40 and CD40 ligand (CD40L) are unable to clear infection with Cryptosporidium parvum and develop cholangitis. Parasites are present in the gut, gall bladder, and biliary tree, and biliary epithelial cells express CD40 on the cell surface. SCID mice infected with C. pa...

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Detalhes bibliográficos
Main Authors: Cosyns, Mary, Tsirkin, Svetlana, Jones, Michelle, Flavell, Richard, Kikutani, Hitoshi, Hayward, Anthony R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC107946/
https://ncbi.nlm.nih.gov/pubmed/9453615
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