Requirement for CD40-CD40 Ligand Interaction for Elimination of Cryptosporidium parvum from Mice

Mice with disrupted genes for CD40 and CD40 ligand (CD40L) are unable to clear infection with Cryptosporidium parvum and develop cholangitis. Parasites are present in the gut, gall bladder, and biliary tree, and biliary epithelial cells express CD40 on the cell surface. SCID mice infected with C. pa...

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Pubblicato in:	Infect Immun
Autori principali:	Cosyns, Mary, Tsirkin, Svetlana, Jones, Michelle, Flavell, Richard, Kikutani, Hitoshi, Hayward, Anthony R.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Fungal and Parasitic Infections
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC107946/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9453615/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.2.603-607.1998
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