Hierarchy of Susceptibility of Dendritic Cell Subsets to Infection by Leishmania major: Inverse Relationship to Interleukin-12 Production

Dendritic cells (DCs) are professional antigen-presenting cells which initiate and regulate T-cell immune responses. Here we show that murine splenic DCs can be ranked on the basis of their ability to phagocytose and harbor the obligately intracellular parasite Leishmania major. CD4(+) CD8(−) DCs ar...

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Detalhes bibliográficos
Main Authors: Henri, Sandrine, Curtis, Joan, Hochrein, Hubertus, Vremec, David, Shortman, Ken, Handman, Emanuela
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC128092/
https://ncbi.nlm.nih.gov/pubmed/12065531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.7.3874-3880.2002
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