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Intranasal Immunization with Killed Unencapsulated Whole Cells Prevents Colonization and Invasive Disease by Capsulated Pneumococci

A whole-cell killed unencapsulated pneumococcal vaccine given by the intranasal route with cholera toxin as an adjuvant was tested in two animal models. This vaccination was highly effective in preventing nasopharyngeal colonization with an encapsulated serotype 6B strain in mice and also conferred...

Szczegółowa specyfikacja

Zapisane w:
Opis bibliograficzny
Wydane w:Infect Immun
Główni autorzy: Malley, Richard, Lipsitch, Marc, Stack, Anne, Saladino, Richard, Fleisher, Gary, Pelton, Steven, Thompson, Claudette, Briles, David, Anderson, Porter
Format: Artigo
Język:Inglês
Wydane: American Society for Microbiology (ASM) 2001
Hasła przedmiotowe:
Dostęp online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98576/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11447162/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.8.4870-4873.2001
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