Intranasal Immunization with Killed Unencapsulated Whole Cells Prevents Colonization and Invasive Disease by Capsulated Pneumococci

A whole-cell killed unencapsulated pneumococcal vaccine given by the intranasal route with cholera toxin as an adjuvant was tested in two animal models. This vaccination was highly effective in preventing nasopharyngeal colonization with an encapsulated serotype 6B strain in mice and also conferred...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Malley, Richard, Lipsitch, Marc, Stack, Anne, Saladino, Richard, Fleisher, Gary, Pelton, Steven, Thompson, Claudette, Briles, David, Anderson, Porter
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
Soggetti:
Microbial Immunity and Vaccines
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC98576/
https://ncbi.nlm.nih.gov/pubmed/11447162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.8.4870-4873.2001
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi