C-Terminal Invariable Domain of VlsE Is Immunodominant but Its Antigenicity Is Scarcely Conserved among Strains of Lyme Disease Spirochetes

VlsE, the variable surface antigen of Borrelia burgdorferi, contains two invariable domains located at the amino and carboxyl terminal ends, respectively, and a central variable domain. In this study, both immunogenicity and antigenic conservation of the C-terminal invariable domain were assessed. M...

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Hlavní autoři: Liang, Fang Ting, Bowers, Lisa C., Philipp, Mario T.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
Microbial Immunity and Vaccines
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC98280/
https://ncbi.nlm.nih.gov/pubmed/11292744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.5.3224-3231.2001
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