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C-Terminal Invariable Domain of VlsE Is Immunodominant but Its Antigenicity Is Scarcely Conserved among Strains of Lyme Disease Spirochetes

VlsE, the variable surface antigen of Borrelia burgdorferi, contains two invariable domains located at the amino and carboxyl terminal ends, respectively, and a central variable domain. In this study, both immunogenicity and antigenic conservation of the C-terminal invariable domain were assessed. M...

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Autors principals: Liang, Fang Ting, Bowers, Lisa C., Philipp, Mario T.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC98280/
https://ncbi.nlm.nih.gov/pubmed/11292744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.5.3224-3231.2001
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