Evidence That the Variable Regions of the Central Domain of VlsE Are Antigenic during Infection with Lyme Disease Spirochetes

It has been postulated that the vls system of the Lyme disease spirochetes contributes to immune evasion through antigenic variation. While it is clear that vlsE undergoes sequence change within its variable regions at a high frequency during the early stages of infection, a definitive role in immun...

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Hlavní autoři: McDowell, John V., Sung, Shian-Ying, Hu, Linden T., Marconi, Richard T.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
Host Response and Inflammation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC128138/
https://ncbi.nlm.nih.gov/pubmed/12117928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.8.4196-4203.2002
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