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C-Terminal Invariable Domain of VlsE Is Immunodominant but Its Antigenicity Is Scarcely Conserved among Strains of Lyme Disease Spirochetes

VlsE, the variable surface antigen of Borrelia burgdorferi, contains two invariable domains located at the amino and carboxyl terminal ends, respectively, and a central variable domain. In this study, both immunogenicity and antigenic conservation of the C-terminal invariable domain were assessed. M...

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Publicado en:Infect Immun
Autores principales: Liang, Fang Ting, Bowers, Lisa C., Philipp, Mario T.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2001
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98280/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11292744/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.5.3224-3231.2001
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