Specific Antibodies to Porphyromonas gingivalis Lys-Gingipain by DNA Vaccination Inhibit Bacterial Binding to Hemoglobin and Protect Mice from Infection

Lys-gingipain (KGP), a lysine-specific cysteine proteinase, is one of the major virulence factors of Porphyromonas gingivalis. Here we examined the involvement of the catalytic domain of KGP (KGP(cd)) in hemoglobin binding by P. gingivalis, using a specific immunoglobulin G (IgG) elicited by the adm...

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Dades bibliogràfiques

Publicat a:	Infect Immun
Autors principals:	Kuboniwa, Masae, Amano, Atsuo, Shizukuishi, Satoshi, Nakagawa, Ichiro, Hamada, Shigeyuki
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2001
Matèries:	Microbial Immunity and Vaccines
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98250/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11292714/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.5.2972-2979.2001
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