Specific Antibodies to Porphyromonas gingivalis Lys-Gingipain by DNA Vaccination Inhibit Bacterial Binding to Hemoglobin and Protect Mice from Infection

Lys-gingipain (KGP), a lysine-specific cysteine proteinase, is one of the major virulence factors of Porphyromonas gingivalis. Here we examined the involvement of the catalytic domain of KGP (KGP(cd)) in hemoglobin binding by P. gingivalis, using a specific immunoglobulin G (IgG) elicited by the adm...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Infect Immun
Hauptverfasser:	Kuboniwa, Masae, Amano, Atsuo, Shizukuishi, Satoshi, Nakagawa, Ichiro, Hamada, Shigeyuki
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2001
Schlagworte:	Microbial Immunity and Vaccines
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC98250/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11292714/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.69.5.2972-2979.2001
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!