Gram-Positive Bacteria Are Potent Inducers of Monocytic Interleukin-12 (IL-12) while Gram-Negative Bacteria Preferentially Stimulate IL-10 Production

Interleukin-10 (IL-10) and IL-12 are two cytokines secreted by monocytes/macrophages in response to bacterial products which have largely opposite effects on the immune system. IL-12 activates cytotoxicity and gamma interferon (IFN-γ) secretion by T cells and NK cells, whereas IL-10 inhibits these f...

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Опубликовано в::	Infect Immun
Главные авторы:	Hessle, Christina, Andersson, Bengt, Wold, Agnes E.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 2000
Предметы:	Host Response and Inflammation
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97646/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10816515/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.6.3581-3586.2000
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