Essential Role of Interleukin-12 (IL-12) and IL-18 for Gamma Interferon Production Induced by Listeriolysin O in Mouse Spleen Cells

The mechanism of gamma interferon (IFN-γ) production induced by listeriolysin O (LLO), a cytolytic virulence factor of Listeria monocytogenes, was analyzed with special reference to the involvement of macrophage-derived cytokines in spleen cells of mice. LLO purified from the culture supernatant of...

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Detalhes bibliográficos
Main Authors: Nomura, Takamasa, Kawamura, Ikuo, Tsuchiya, Kohsuke, Kohda, Chikara, Baba, Hisashi, Ito, Yutaka, Kimoto, Terumi, Watanabe, Isao, Mitsuyama, Masao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127750/
https://ncbi.nlm.nih.gov/pubmed/11854182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.70.3.1049-1055.2002
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