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Directed evolution of a recombinase for improved genomic integration at a native human sequence
We previously established that a unidirectional site-specific recombinase, the phage φC31 integrase, can mediate integration into mammalian chromosomes. The enzyme directs integration of plasmids bearing the phage attB recognition site into pseudo attP sites, a set of native sequences related to the...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Oxford University Press
2001
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC97615/ https://ncbi.nlm.nih.gov/pubmed/11812835 |
| Etiketak: |
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