Site-Specific Genomic Integration in Mammalian Cells Mediated by Phage φC31 Integrase

We previously established that the phage φC31 integrase, a site-specific recombinase, mediates efficient integration in the human cell environment at attB and attP phage attachment sites on extrachromosomal vectors. We show here that phage attP sites inserted at various locations in human and mouse...

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Библиографические подробности
Главные авторы: Thyagarajan, Bhaskar, Olivares, Eric C., Hollis, Roger P., Ginsburg, Daniel S., Calos, Michele P.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2001
Предметы:
DNA Dynamics and Chromosome Structure
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC87055/
https://ncbi.nlm.nih.gov/pubmed/11359900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.12.3926-3934.2001
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