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Evolution of variants of yeast site-specific recombinase Flp that utilize native genomic sequences as recombination target sites
As a tool in directed genome manipulations, site-specific recombination is a double-edged sword. Exquisite specificity, while highly desirable, makes it imperative that the target site be first inserted at the desired genomic locale before it can be manipulated. We describe a combination of computat...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2006
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1635253/ https://ncbi.nlm.nih.gov/pubmed/17003057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl548 |
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