Flavones inhibit the hexameric replicative helicase RepA
Helicases couple the hydrolysis of nucleoside triphosphates (NTPs) to the unwinding of double-stranded nucleic acids and are essential in DNA metabolism. Thus far, no inhibitors are known for helicases except heliquinomycin isolated from Streptomyces sp. As the three-dimensional structure of the hex...
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97556/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11812837/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.24.5058 |
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