Blockade of Costimulation Prevents Infection-Induced Immunopathology in Interleukin-10-Deficient Mice

Interleukin-10 (IL-10) is associated with inhibition of cell-mediated immunity and downregulation of the expression of costimulatory molecules required for T-cell activation. When IL-10-deficient (IL-10KO) mice are infected with Toxoplasma gondii, they succumb to a T-cell-mediated shock-like reactio...

Description complète

Détails bibliographiques

Publié dans:	Infect Immun
Auteurs principaux:	Villegas, Eric N., Wille, Ulrike, Craig, Linden, Linsley, Peter S., Rennick, Donna M., Peach, Robert, Hunter, Christopher A.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2000
Sujets:	Fungal and Parasitic Infections
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97495/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10768980/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.5.2837-2844.2000
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!