Blockade of Costimulation Prevents Infection-Induced Immunopathology in Interleukin-10-Deficient Mice
Interleukin-10 (IL-10) is associated with inhibition of cell-mediated immunity and downregulation of the expression of costimulatory molecules required for T-cell activation. When IL-10-deficient (IL-10KO) mice are infected with Toxoplasma gondii, they succumb to a T-cell-mediated shock-like reactio...
Kaydedildi:
| Yayımlandı: | Infect Immun |
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| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology (ASM)
2000
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97495/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10768980/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.5.2837-2844.2000 |
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