Blockade of Costimulation Prevents Infection-Induced Immunopathology in Interleukin-10-Deficient Mice

Interleukin-10 (IL-10) is associated with inhibition of cell-mediated immunity and downregulation of the expression of costimulatory molecules required for T-cell activation. When IL-10-deficient (IL-10KO) mice are infected with Toxoplasma gondii, they succumb to a T-cell-mediated shock-like reactio...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Villegas, Eric N., Wille, Ulrike, Craig, Linden, Linsley, Peter S., Rennick, Donna M., Peach, Robert, Hunter, Christopher A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Fungal and Parasitic Infections
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97495/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10768980/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.5.2837-2844.2000
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