Xanthine Oxidase Contributes to Host Defense against Burkholderia cepacia in the p47(phox−/−) Mouse Model of Chronic Granulomatous Disease

Chronic granulomatous disease (CGD) is an inherited disorder of the NADPH oxidase in which phagocytes are defective in generating superoxide and downstream microbicidal reactive oxidants, leading to recurrent life-threatening bacterial and fungal infections. Xanthine oxidase (XO) is another enzyme k...

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Bibliografski detalji
Glavni autori: Segal, Brahm H., Sakamoto, Nobuaki, Patel, Mayur, Maemura, Kosei, Klein, Andrew S., Holland, Steven M., Bulkley, Gregory B.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
Teme:
Host Response and Inflammation
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC97432/
https://ncbi.nlm.nih.gov/pubmed/10722648
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