Xanthine Oxidase Contributes to Host Defense against Burkholderia cepacia in the p47(phox−/−) Mouse Model of Chronic Granulomatous Disease

Chronic granulomatous disease (CGD) is an inherited disorder of the NADPH oxidase in which phagocytes are defective in generating superoxide and downstream microbicidal reactive oxidants, leading to recurrent life-threatening bacterial and fungal infections. Xanthine oxidase (XO) is another enzyme k...

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Autors principals: Segal, Brahm H., Sakamoto, Nobuaki, Patel, Mayur, Maemura, Kosei, Klein, Andrew S., Holland, Steven M., Bulkley, Gregory B.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
Matèries:
Host Response and Inflammation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC97432/
https://ncbi.nlm.nih.gov/pubmed/10722648
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