Xanthine Oxidase Contributes to Host Defense against Burkholderia cepacia in the p47(phox−/−) Mouse Model of Chronic Granulomatous Disease

Chronic granulomatous disease (CGD) is an inherited disorder of the NADPH oxidase in which phagocytes are defective in generating superoxide and downstream microbicidal reactive oxidants, leading to recurrent life-threatening bacterial and fungal infections. Xanthine oxidase (XO) is another enzyme k...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Infect Immun
Hauptverfasser:	Segal, Brahm H., Sakamoto, Nobuaki, Patel, Mayur, Maemura, Kosei, Klein, Andrew S., Holland, Steven M., Bulkley, Gregory B.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2000
Schlagworte:	Host Response and Inflammation
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97432/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10722648/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.4.2374-2378.2000
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!