Xanthine Oxidase Contributes to Host Defense against Burkholderia cepacia in the p47(phox−/−) Mouse Model of Chronic Granulomatous Disease

Chronic granulomatous disease (CGD) is an inherited disorder of the NADPH oxidase in which phagocytes are defective in generating superoxide and downstream microbicidal reactive oxidants, leading to recurrent life-threatening bacterial and fungal infections. Xanthine oxidase (XO) is another enzyme k...

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Опубліковано в::	Infect Immun
Автори:	Segal, Brahm H., Sakamoto, Nobuaki, Patel, Mayur, Maemura, Kosei, Klein, Andrew S., Holland, Steven M., Bulkley, Gregory B.
Формат:	Artigo
Мова:	Inglês
Опубліковано:	American Society for Microbiology (ASM) 2000
Предмети:	Host Response and Inflammation
Онлайн доступ:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97432/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10722648/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.4.2374-2378.2000
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