Xanthine Oxidase Contributes to Host Defense against Burkholderia cepacia in the p47(phox−/−) Mouse Model of Chronic Granulomatous Disease

Chronic granulomatous disease (CGD) is an inherited disorder of the NADPH oxidase in which phagocytes are defective in generating superoxide and downstream microbicidal reactive oxidants, leading to recurrent life-threatening bacterial and fungal infections. Xanthine oxidase (XO) is another enzyme k...

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Detalhes bibliográficos
Main Authors: Segal, Brahm H., Sakamoto, Nobuaki, Patel, Mayur, Maemura, Kosei, Klein, Andrew S., Holland, Steven M., Bulkley, Gregory B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC97432/
https://ncbi.nlm.nih.gov/pubmed/10722648
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