Reduced Virulence of HWP1-Deficient Mutants of Candida albicans and Their Interactions with Host Cells

The Candida albicans gene HWP1 encodes a surface protein that is required for normal hyphal development in vitro. We used mutants lacking one or both alleles of HWP1 to investigate the role of this gene in virulence. Mice infected intravenously with the homozygous hwp1 null mutant, CAL3, survived a...

Descripció completa

Dades bibliogràfiques

Publicat a:	Infect Immun
Autors principals:	Tsuchimori, Noboru, Sharkey, Laura L., Fonzi, William A., French, Samuel W., Edwards, John E., Filler, Scott G.
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2000
Matèries:	Fungal and Parasitic Infections
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97378/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10722594/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.4.1997-2002.2000
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!