Reduced Virulence of HWP1-Deficient Mutants of Candida albicans and Their Interactions with Host Cells

The Candida albicans gene HWP1 encodes a surface protein that is required for normal hyphal development in vitro. We used mutants lacking one or both alleles of HWP1 to investigate the role of this gene in virulence. Mice infected intravenously with the homozygous hwp1 null mutant, CAL3, survived a...

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Detalles Bibliográficos

Publicado en:	Infect Immun
Principais autores:	Tsuchimori, Noboru, Sharkey, Laura L., Fonzi, William A., French, Samuel W., Edwards, John E., Filler, Scott G.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2000
Assuntos:	Fungal and Parasitic Infections
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC97378/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10722594/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.4.1997-2002.2000
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