Reduced Virulence of HWP1-Deficient Mutants of Candida albicans and Their Interactions with Host Cells

The Candida albicans gene HWP1 encodes a surface protein that is required for normal hyphal development in vitro. We used mutants lacking one or both alleles of HWP1 to investigate the role of this gene in virulence. Mice infected intravenously with the homozygous hwp1 null mutant, CAL3, survived a...

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Bibliografiske detaljer
Main Authors: Tsuchimori, Noboru, Sharkey, Laura L., Fonzi, William A., French, Samuel W., Edwards, John E., Filler, Scott G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Fungal and Parasitic Infections
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC97378/
https://ncbi.nlm.nih.gov/pubmed/10722594
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