Phase 2 Clinical Trial of Attenuated Salmonella enterica Serovar Typhi Oral Live Vector Vaccine CVD 908-htrA in U.S. Volunteers

Salmonella enterica serovar Typhi strain CVD 908-htrA is a live attenuated strain which may be useful as an improved oral typhoid vaccine and as a vector for cloned genes of other pathogens. We conducted a phase 2 trial in which 80 healthy adults received one of two dosage levels of CVD 908-htrA in...

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Главные авторы: Tacket, Carol O., Sztein, Marcelo B., Wasserman, Steven S., Losonsky, Genevieve, Kotloff, Karen L., Wyant, Timothy L., Nataro, James P., Edelman, Robert, Perry, Judith, Bedford, Philip, Brown, David, Chatfield, Stephen, Dougan, Gordon, Levine, Myron M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2000
Предметы:
Microbial Immunity and Vaccines
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC97267/
https://ncbi.nlm.nih.gov/pubmed/10678926
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