Phase 2 Clinical Trial of Attenuated Salmonella enterica Serovar Typhi Oral Live Vector Vaccine CVD 908-htrA in U.S. Volunteers

Salmonella enterica serovar Typhi strain CVD 908-htrA is a live attenuated strain which may be useful as an improved oral typhoid vaccine and as a vector for cloned genes of other pathogens. We conducted a phase 2 trial in which 80 healthy adults received one of two dosage levels of CVD 908-htrA in...

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Detalhes bibliográficos
Main Authors: Tacket, Carol O., Sztein, Marcelo B., Wasserman, Steven S., Losonsky, Genevieve, Kotloff, Karen L., Wyant, Timothy L., Nataro, James P., Edelman, Robert, Perry, Judith, Bedford, Philip, Brown, David, Chatfield, Stephen, Dougan, Gordon, Levine, Myron M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC97267/
https://ncbi.nlm.nih.gov/pubmed/10678926
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