Expression and immunogenicity of pertussis toxin S1 subunit-tetanus toxin fragment C fusions in Salmonella typhi vaccine strain CVD 908.

Salmonella typhi vaccine strain CVD 908 can deliver heterologous antigens to the host immune system following mucosal immunization. Stable expression of foreign proteins in Salmonella cells often requires antigen-specific engineering strategies. Fusion of antigens to stabilizing proteins has proven...

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Bibliografiske detaljer
Main Authors: Barry, E M, Gomez-Duarte, O, Chatfield, S, Rappuoli, R, Pizza, M, Losonsky, G, Galen, J, Levine, M M
Format: Artigo
Sprog:Inglês
Udgivet: 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC174353/
https://ncbi.nlm.nih.gov/pubmed/8926085
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