Expression and immunogenicity of pertussis toxin S1 subunit-tetanus toxin fragment C fusions in Salmonella typhi vaccine strain CVD 908.

Salmonella typhi vaccine strain CVD 908 can deliver heterologous antigens to the host immune system following mucosal immunization. Stable expression of foreign proteins in Salmonella cells often requires antigen-specific engineering strategies. Fusion of antigens to stabilizing proteins has proven...

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Autores principales: Barry, E M, Gomez-Duarte, O, Chatfield, S, Rappuoli, R, Pizza, M, Losonsky, G, Galen, J, Levine, M M
Formato: Artigo
Lenguaje:Inglês
Publicado: 1996
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC174353/
https://ncbi.nlm.nih.gov/pubmed/8926085
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