Expression of Herpes Simplex Virus Thymidine Kinase in Toxoplasma gondii Attenuates Tachyzoite Virulence in Mice

We tested the virulence in mice of Toxoplasma gondii RH strain tachyzoites containing various copies of the chloramphenicol acetyl transferase-herpes simplex virus thymidine kinase fusion sequence (CAT-HSTK). Tachyzoite isolates containing ≥five copies of the fusion sequence were not lethal to femal...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Radke, Jay R., White, Michael W.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Microbial Immunity and Vaccines
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96883/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10496908/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.10.5292-5297.1999
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!