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Expression of Herpes Simplex Virus Thymidine Kinase in Toxoplasma gondii Attenuates Tachyzoite Virulence in Mice
We tested the virulence in mice of Toxoplasma gondii RH strain tachyzoites containing various copies of the chloramphenicol acetyl transferase-herpes simplex virus thymidine kinase fusion sequence (CAT-HSTK). Tachyzoite isolates containing ≥five copies of the fusion sequence were not lethal to femal...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
1999
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC96883/ https://ncbi.nlm.nih.gov/pubmed/10496908 |
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