Expression of Herpes Simplex Virus Thymidine Kinase in Toxoplasma gondii Attenuates Tachyzoite Virulence in Mice

We tested the virulence in mice of Toxoplasma gondii RH strain tachyzoites containing various copies of the chloramphenicol acetyl transferase-herpes simplex virus thymidine kinase fusion sequence (CAT-HSTK). Tachyzoite isolates containing ≥five copies of the fusion sequence were not lethal to femal...

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Bibliografische gegevens

Gepubliceerd in:	Infect Immun
Hoofdauteurs:	Radke, Jay R., White, Michael W.
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Microbiology (ASM) 1999
Onderwerpen:	Microbial Immunity and Vaccines
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96883/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10496908/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.10.5292-5297.1999
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