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Zonula Occludens Toxin Is a Powerful Mucosal Adjuvant for Intranasally Delivered Antigens

Zonula occludens toxin (Zot) is produced by toxigenic strains of Vibrio cholerae and has the ability to reversibly alter intestinal epithelial tight junctions, allowing the passage of macromolecules through the mucosal barrier. In the present study, we investigated whether Zot could be exploited to...

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Autori principali: Marinaro, Mariarosaria, di Tommaso, Annalisa, Uzzau, Sergio, Fasano, Alessio, de Magistris, Maria Teresa
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC96458/
https://ncbi.nlm.nih.gov/pubmed/10024572
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