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Zonula Occludens Toxin Acts as an Adjuvant through Different Mucosal Routes and Induces Protective Immune Responses

Zonula occludens toxin (Zot) is produced by Vibrio cholerae and has the ability to increase mucosal permeability by reversibly affecting the structure of tight junctions. Because of this property, Zot is a promising tool for mucosal drug and antigen (Ag) delivery. Here we show that Zot acts as a muc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Marinaro, Mariarosaria, Fasano, Alessio, De Magistris, Maria Teresa
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC152047/
https://ncbi.nlm.nih.gov/pubmed/12654806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.4.1897-1902.2003
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