Clostridium difficile Toxin A Carboxyl-Terminus Peptide Lacking ADP-Ribosyltransferase Activity Acts as a Mucosal Adjuvant

The receptor binding domains of the most potent mucosal adjuvants, bacterial toxins and plant lectins, are organized in repeat units to recognize specific sugar residues. The lectin-like structure of the C-terminal region of Clostridium difficile toxin A prompted us to investigate the mucosal adjuva...

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Detalhes bibliográficos
Main Authors: Castagliuolo, Ignazio, Sardina, Marina, Brun, Paola, DeRos, Chiara, Mastrotto, Cristina, Lovato, Laura, Palù, Giorgio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC387895/
https://ncbi.nlm.nih.gov/pubmed/15102793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.5.2827-2836.2004
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