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Prevalence and Characterization of a Binary Toxin (Actin-Specific ADP-Ribosyltransferase) from Clostridium difficile

In addition to the two large clostridial cytotoxins (TcdA and TcdB), some strains of Clostridium difficile also produce an actin-specific ADP-ribosyltransferase, called binary toxin CDT. We used a PCR method and Southern blotting for the detection of genes encoding the enzymatic (CDTa) and binding (...

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Detalhes bibliográficos
Main Authors: Gonçalves, Carina, Decré, Dominique, Barbut, Frédéric, Burghoffer, Béatrice, Petit, Jean-Claude
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC404597/
https://ncbi.nlm.nih.gov/pubmed/15131151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.42.5.1933-1939.2004
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