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Modulation of intestinal tight junctions by Zonula occludens toxin permits enteral administration of insulin and other macromolecules in an animal model.

The intestinal epithelium represents the major barrier to absorption of orally administered drugs and peptides into the systemic circulation. Entry of molecules through the paracellular pathway is restricted by tight junctions. We have previously reported that these structures can be modulated by Zo...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Fasano, A, Uzzau, S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 1997
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507928/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9077522/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119271
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