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Zonula Occludens Toxin Is a Powerful Mucosal Adjuvant for Intranasally Delivered Antigens

Zonula occludens toxin (Zot) is produced by toxigenic strains of Vibrio cholerae and has the ability to reversibly alter intestinal epithelial tight junctions, allowing the passage of macromolecules through the mucosal barrier. In the present study, we investigated whether Zot could be exploited to...

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Auteurs principaux: Marinaro, Mariarosaria, di Tommaso, Annalisa, Uzzau, Sergio, Fasano, Alessio, de Magistris, Maria Teresa
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1999
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC96458/
https://ncbi.nlm.nih.gov/pubmed/10024572
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