Preliminary Assessment of the Safety and Immunogenicity of a New CTXΦ-Negative, Hemagglutinin/Protease-Defective El Tor Strain as a Cholera Vaccine Candidate

Vibrio cholerae 638 (El Tor, Ogawa), a new CTXΦ-negative hemagglutinin/protease-defective strain that is a cholera vaccine candidate, was examined for safety and immunogenicity in healthy adult volunteers. In a double-blind placebo-controlled study, no significant adverse reactions were observed in...

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Detaylı Bibliyografya
Asıl Yazarlar: Benítez, Jorge A., García, Luis, Silva, Anisia, García, Hilda, Fando, Rafael, Cedré, Barbara, Pérez, Antonio, Campos, Javier, Rodríguez, Boris L., Pérez, José L., Valmaseda, Tania, Pérez, Oliver, Pérez, Alberto, Ramírez, Margarita, Ledón, Talena, Jidy, Manuel Díaz, Lastre, Miriam, Bravo, Laura, Sierra, Gustavo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 1999
Konular:
Microbial Immunity and Vaccines
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC96352/
https://ncbi.nlm.nih.gov/pubmed/9916056
Etiketler: Etiketle
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