Oral Administration of Influenza Vaccine in Combination with the Adjuvants LT-K63 and LT-R72 Induces Potent Immune Responses Comparable to or Stronger than Traditional Intramuscular Immunization

Mucosal immunization strategies are actively being pursued in the hopes of improving the efficacy of vaccines against the influenza virus. Our group investigated the oral immunization of mice via intragastric gavage with influenza hemagglutinin (HA) combined with mutant Escherichia coli heat-labile...

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Main Authors: Barackman, John D., Ott, Gary, Pine, Samuel, O'Hagan, Derek T.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2001
Teme:
Immune-Mediated Responses and Disorders
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC96119/
https://ncbi.nlm.nih.gov/pubmed/11329476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.8.3.652-657.2001
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