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DNA-vaccination via tattooing induces stronger humoral and cellular immune responses than intramuscular delivery supported by molecular adjuvants

Tattooing is one of a number of DNA delivery methods which results in an efficient expression of an introduced gene in the epidermal and dermal layers of the skin. The tattoo procedure causes many minor mechanical injuries followed by hemorrhage, necrosis, inflammation and regeneration of the skin a...

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Detalhes bibliográficos
Main Authors: Pokorna, Dana, Rubio, Ivonne, Müller, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2267179/
https://ncbi.nlm.nih.gov/pubmed/18257910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-0556-6-4
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