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Cationic microparticles: A potent delivery system for DNA vaccines

An approach involving the preparation of biodegradable microparticles with a cationic surface was developed to improve the delivery of adsorbed DNA into antigen-presenting cells after i.m. injection. The microparticles released intact and functional DNA over 2 weeks in vitro. In addition, the microp...

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Autors principals: Singh, Manmohan, Briones, Maylene, Ott, Gary, O'Hagan, Derek
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC15413/
https://ncbi.nlm.nih.gov/pubmed/10639162
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