Oral Administration of Influenza Vaccine in Combination with the Adjuvants LT-K63 and LT-R72 Induces Potent Immune Responses Comparable to or Stronger than Traditional Intramuscular Immunization

Mucosal immunization strategies are actively being pursued in the hopes of improving the efficacy of vaccines against the influenza virus. Our group investigated the oral immunization of mice via intragastric gavage with influenza hemagglutinin (HA) combined with mutant Escherichia coli heat-labile...

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Detalhes bibliográficos
Main Authors: Barackman, John D., Ott, Gary, Pine, Samuel, O'Hagan, Derek T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Immune-Mediated Responses and Disorders
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC96119/
https://ncbi.nlm.nih.gov/pubmed/11329476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.8.3.652-657.2001
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