Sequential Inactivation of rdxA (HP0954) and frxA (HP0642) Nitroreductase Genes Causes Moderate and High-Level Metronidazole Resistance in Helicobacter pylori

Helicobacter pylori is a human-pathogenic bacterial species that is subdivided geographically, with different genotypes predominating in different parts of the world. Here we test and extend an earlier conclusion that metronidazole (Mtz) resistance is due to mutation in rdxA (HP0954), which encodes...

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Detalhes bibliográficos
Main Authors: Jeong, Jin-Yong, Mukhopadhyay, Asish K., Dailidiene, Daiva, Wang, Yipeng, Velapatiño, Billie, Gilman, Robert H., Parkinson, Alan J., Nair, G. Balakrish, Wong, Benjamin C. Y., Lam, Shiu Kum, Mistry, Rajesh, Segal, Isidore, Yuan, Yuan, Gao, Hua, Alarcon, Teresa, Brea, MaNuel Lopez, Ito, Yoshiyuki, Kersulyte, Dangeruta, Lee, Hae-Kyung, Gong, Yan, Goodwin, Avery, Hoffman, Paul S., Berg, Douglas E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Population Genetics and Evolution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC94655/
https://ncbi.nlm.nih.gov/pubmed/10960091
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