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The fdxA Ferredoxin Gene Can Down-Regulate frxA Nitroreductase Gene Expression and Is Essential in Many Strains of Helicobacter pylori

Very few examples of metabolic regulation are known in the gastric pathogen Helicobacter pylori. An unanticipated case was suggested, however, upon finding two types of metronidazole (Mtz)-susceptible strains: type I, in which frxA (which encodes a nitroreductase that contributes to Mtz susceptibili...

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Detalhes bibliográficos
Main Authors: Mukhopadhyay, Asish K., Jeong, Jin-Yong, Dailidiene, Daiva, Hoffman, Paul S., Berg, Douglas E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC154416/
https://ncbi.nlm.nih.gov/pubmed/12700272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.9.2927-2935.2003
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