Inhibitory Effects of Small-Molecule CCR5 Antagonists on Human Immunodeficiency Virus Type 1 Envelope-Mediated Membrane Fusion and Viral Replication

We established a human immunodeficiency virus type 1 (HIV-1) envelope (Env)-mediated membrane fusion assay and examined the small-molecule CCR5 antagonist TAK-779 and its derivatives for their inhibitory effects on HIV-1 Env-mediated membrane fusion and viral replication. The membrane fusion assay i...

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Detalhes bibliográficos
Main Authors: Takashima, Katsunori, Miyake, Hiroshi, Furuta, Rika A., Fujisawa, Jun-Ichi, Iizawa, Yuji, Kanzaki, Naoyuki, Shiraishi, Mitsuru, Okonogi, Kenji, Baba, Masanori
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC90865/
https://ncbi.nlm.nih.gov/pubmed/11709336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.12.3538-3543.2001
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