טוען...
Dicyclic and Tricyclic Diaminopyrimidine Derivatives as Potent Inhibitors of Cryptosporidium parvum Dihydrofolate Reductase: Structure-Activity and Structure-Selectivity Correlations
A structurally diverse library of 93 lipophilic di- and tricyclic diaminopyrimidine derivatives was tested for the ability to inhibit recombinant dihydrofolate reductase (DHFR) cloned from human and bovine isolates of Cryptosporidium parvum (J. R. Vásquez et al., Mol. Biochem. Parasitol. 79:153–165,...
שמור ב:
| Main Authors: | , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Microbiology
2001
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| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC90829/ https://ncbi.nlm.nih.gov/pubmed/11709300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.12.3293-3303.2001 |
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