Association of Genetic Mutations in Plasmodium vivax dhfr with Resistance to Sulfadoxine-Pyrimethamine: Geographical and Clinical Correlates

Mutations in the Plasmodium falciparum gene (dhfr) encoding dihydrofolate reductase are associated with resistance to antifols. Plasmodium vivax, the more prevalent malaria parasite in Asia and the Americas, is considered antifol resistant. Functional polymorphisms in the dhfr gene of P. vivax (pvdh...

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הוצא לאור ב:	Antimicrob Agents Chemother
Principais autores:	Imwong, Mallika, Pukrittakayamee, Sasithon, Looareesuwan, Sornchai, Pasvol, Geoffrey, Poirreiz, Jean, White, Nicholas J., Snounou, Georges
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 2001
נושאים:	Mechanisms of Resistance
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90792/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11600366/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.11.3122-3127.2001
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